Lyme Disease Clinical Guidance
This clinical guidance document addresses the diagnosis, management and treatment of early localized Lyme disease, based on the best available evidence. Ontario Health developed this guidance in collaboration with Public Health Ontario, clinical experts, patients, and caregivers from across the province.
If you are a community pharmacist you can learn about the assessment and prescribing of appropriate antibiotic prophylaxis to prevent Lyme disease following a tick bite using guidance for community pharmacists developed by Public Health Ontario, in collaboration with Ontario Health.
Last Updated: June 04, 2026
