Genetic Test Details

Loeys-Dietz Syndrome

Test Information

Titre
Loeys-Dietz Syndrome
Catégorie
Connective Tissue , Cardiogenetics
Sub Category
Loeys-Dietz Syndrome
Gene/Platform/Region List
SLC2A10, SMAD2, SMAD3, TGFB2, TGFB3, TGFBR1, TGFBR2
Test type
Gene Panel
Samples Accepted
DNA , Blood , Cultured Cells , CVS , Amniocyte
Indications
Carrier Cascade Testing , Diagnosis , Prenatal
Test Methodology
Sequencing , CNV
Methodology Notes
Oligonucleotide based target capture, sanger sequencing for any clinically significant regions that are not captured and/or have insufficient coverage, MLPA (TGFBR1 and TGFBR2).
Disease/Condition
Loeys-Dietz Syndrome, Loeys-Dietz Aortic Aneurysm Syndrome, Marfan syndrome type 2

Dernière Mise à Jour: 18 juin 2025