Genetic Test Details

Noonan Syndrome and RASopathies

Test Information

Title
Noonan Syndrome and RASopathies
Category
Cardiogenetics , Immunity , Multiple Congenital Anomalies
Sub Category
Noonan Syndrome and RASopathies
Gene/Platform/Region List
BRAF, CBL, HRAS, KRAS, LZTR1, MAP2K1, MAP2K2, NRAS, PTPN11, RAF1, RIT1, SHOC2, SOS1, SOS2, SPRED1 (Dosage ONLY)
Test type
Gene Panel
Samples Accepted
DNA , Blood , DNA (Not Accepted for MLPA)
Indications
Diagnosis , Prenatal
Test Methodology
Sequencing , CNV
Methodology Notes
NGS; MLPA of SPRED1
Disease/Condition
Noonan syndrome, Noonan-like  syndrome, Costello syndrome, CFC syndrome, LEOPARD syndrome, Legius syndrome

Last Updated: June 23, 2025