HTA Details

Wire-Free, Nonradioactive Localization Techniques to Guide Surgical Excision of Nonpalpable Breast Tumours

Publication date
2023-May-17
Status
Final
Topic Area
Cancer
Recommendation

Final Recommendation

  • Ontario Health, based on guidance from the Ontario Health Technology Advisory Committee, recommends publicly funding wire-free, nonradioactive localization techniques for the localization of nonpalpable breast tumours.
Ministry Response
The Ministry of Health endorses this recommendation.

The standard treatment for nonpalpable breast tumours is to surgically remove them. But because these tumours are so small, it is necessary to pinpoint their location before surgery by implanting a marker inside the tumour using mammogram or ultrasound guidance. This procedure is called localization.

The current localization techniques used in Ontario are wire-guided localization and radioactive seed localization, both of which have some limitations. Wire-free, nonradioactive localization is a new type of localization that overcomes these limitations. Two types are now being used at some hospitals in Ontario: magnetic seed localization and reflector-guided localization.

This health technology assessment looked at how safe and effective wire-free, nonradioactive localization techniques to guide surgical removal of nonpalpable breast tumours are. It also looked at the budget impact of publicly funding wire-free, nonradioactive localization techniques and at the experiences, preferences, and values of people who have undergone a localization procedure for the excision of a nonpalpable breast tumour.

Last Updated: February 24, 2026