PET Scans Ontario Program Governance

Committee Review Process

Regular review of scientific evidence helps identify and evaluate emerging indications - clinical situations where PET may impact patient care. These reviews help make sure we continue to meet the needs of Ontario patients.

The PET Steering Committee’s recommendations about the appropriate use of PET are based on review of:

• evidence in scientific literature
• outcomes data from Ontario's evidence-building programs, such as the PET Registry
• engagement with treating clinician experts on the potential impact to patient management

The committee also welcomes recommendations or requests regarding the assessment of potential indications. Use the contact form to request a review of emerging evidence.

Consideration of Scientific Evidence

• Evidence from scientific literature is considered based on the potential impact of PET on patient management.
• Results from methodologically rigorous large studies are considered stronger evidence than results from less rigorous and/or smaller studies.
• Special consideration may be given for indications with weak but compelling evidence (for example, retrospective studies or smaller cohort trials with demonstration of significant impact on patient care).
• Evidence of sensitivity, specificity or accuracy alone - without evidence of impact on patient management - is not sufficient to recommend an indication.

Prioritization of Indications

If the committee must decide which indications to review in which order, it will:

• prioritize indications that affect larger patient populations and/or with greater potential impact on patient care
• consider the date the request was submitted