GDT Ontario Health Testing Eligibility
Cardiomyopathy and Arrhythmia
GTD Indications
Diagnosis
Carrier / Cascade Testing
Prenatal
GTD Samples Accepted
Blood
DNA
Cultured Cells
Amniocyte
CVS
GTD Test Methodology
CNV
Sequencing
GTD Methodology Notes
Oligonucleotide based target capture, Sanger if low coverage, MLPA (BAG3, MYH7, MYBPC3, PKP2, and TNNT2)
Generic Test name (cms title)
Cardiomyopathy
GTD Test type
Gene Panel
GTD Location
Children's Hospital of Eastern Ontario
GTD Gene/Platform/Region List
BAG3, DES, DSC2, DSG2, DSP, FLNC, GLA, JUP, LAMP2, LMNA, MYH7, MYL2, MYL3, NEXN, PKP2, PLN, PRKAG2, RBM20, SCN5A, TMEM (43 c.1073C>T), TNNI3, TNNT2, TPM1, TTN, TTR, ACTC1, ACTN2, MYBPC3, TNNC1, VCL
GTD Category
Cardiogenetics
GTD Disease/Condition
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC), Uhl anomaly and right ventricular dysplasia, arrhythmogenic right ventricular dysplasia (ARVD), Hypertrophic Cardiomyopathy (HCM), Heritable hypertrophic cardiomyopathy, Familial HCM, Cardiomyopathy familial hypertrophic, Dilated cardiomyopathy (DCM)