Thrombosis
| Test Information | |
|---|---|
| Test Name | Thrombosis |
| Lab (Location) | University Health Network |
| Category | Hematology |
| Subcategory | Thrombosis |
| Gene/Platform/Region List | F2 (NM_00506.4:c.*_97G>A (Prothrombin G20210A)), F5 (NM_000130.3: p.Arg534Gln (Factor V Leiden R506Q)), MTHFR (NM_005957.3: p.Ala222Val (MTHFR C677T)) |
| Test type | Targeted Variant |
| Samples Accepted | Blood, DNA, Saliva |
| Indications Diagnosis | Diagnosis, Carrier / Cascade Testing |
| Test Methodology | Sequencing |
| Methodology Notes | Targeted Mutations; FVL/prothrombin/F2 (G20210GA) |
| Diseases/Conditions | prothrombin deficiency, Prothrombin Thrombophilia, F2-related thrombophilia, factor II-related thrombophilia, prothrombin 20210G>A thrombophilia, FII, factor V leiden deficiency, factor V leiden thrombophilia, FV |
| Notes | Saliva samples must be provided in oragene, OG-600 kits; UHN does not provide collection kits but they can be obtained directly from DNA genotek (www.dnagenotek.com) |